DPPA3 (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDPPA3 (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL
Concentrationvial concentration: 0.28
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis DPPA3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 145-179 amino acids from the C-terminal region of human DPPA3. Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects materna
Immunogenn/a
Other Names[Developmental pluripotency-associated protein 3; Stella-related protein; DPPA3; STELLAR]
Gene, Accession #[DPPA3], Gene ID: 359787, NCBI: NP_954980.1, UniProt: Q6W0C5
Catalog #MBS9211508
Price$150
Order / More InfoDPPA3 (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPayer B.,et al.Curr. Biol. 13:2110-2117(2003). Clark A.T.,et al.Stem Cells 22:169-179(2004). Julaton V.T.,et al.Hum. Mol. Genet. 20:2238-2250(2011). Bowles J.,et al.Cytogenet. Genome Res. 101:261-265(2003).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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