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Antigenic Specificity | PANK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PANK2 protein. PANK2 gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PANK2 protein |
Other Names | [Rabbit PANK2; Pantothenate kinase 2, mitochondrial; hPanK2; Pantothenic acid kinase 2] |
Gene, Accession # | [PANK2], Gene ID: 80025, UniProt: Q9BZ23 |
Catalog # | MBS9710368 |
Price | $130, $220, $325 |
Order / More Info | PANK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |