MCAM Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMCAM
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPlays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 447-646 of human MCAM (NP 006491.2).
Other Names[CD146; MUC18; HEMCAM; METCAM; MelCAM]
Gene, Accession #[MCAM], NCBI: P43121.2, UniProt: P43121
Catalog #MBS8544700
Price$280
Order / More InfoMCAM Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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