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Antigenic Specificity | Bak |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Bak antibody detects endogenous levels of total Bak. Bak1 In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. Belongs to the Bcl-2 family. Interacts with BCL2A1. Homodimer. Formation of the homodimer is zinc-dependent. Forms heterodimers with BCL2, E1B 19k protein, and BCL2L1 isoform Bcl-X(L). Interacts with myxoma virus protein M11L |
Immunogen | Immunogen: A synthesized peptide derived from human Bak |
Other Names | [Apoptosis regulator BAK; BAK; BAK-LIKE; BAK1; Bcl-2 homologous antagonist/killer; Bcl-2-like protein 7; BCL2-antagonist/killer 1; Bcl2-L-7; BCL2-like 7 protein; BCL2L7; CDN1; MGC117255; MGC3887; pro-apoptotic protein BAK] |
Gene, Accession # | [Bak], Gene ID: 578, NCBI: NP_001179.1, UniProt: Q16611 |
Catalog # | MBS8510614 |
Price | $290 |
Order / More Info | Bak Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |