Peroxiredoxin 4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPeroxiredoxin 4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for Peroxiredoxin-4(PRDX4) detection. Tested with WB in Human, Mouse, Rat. Background: PRDX4(peroxiredoxin 4) also known as AOE37-2. The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. Functional analysis showed that PRDX4 protects glutamine synthetase from inactivation. Yeast 2-hybrid, immunoprecipitation, and immunoblot analyses indicated that PRDX4 and PRDX1 are capable of homodimerization and heterodimerization with each other but not with the mitochondrial PRDX3. Gel mobility shift and immunoblot analysis found that PRDX4 depletes NFKB binding activity together with a reduction in the amounts of p50, p65, and phosphorylated IKBA, as well as a red
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Peroxiredoxin 4 (253-271aa SETIIPDPAGKLKYFDKLN), identical to the related mouse and rat sequences.
Other Names[Peroxiredoxin-4; peroxiredoxin 4; Antioxidant enzyme 372; Antioxidant enzyme AOE372; AOE37 2; AOE37-2; AOE372; EC 1.11.1.15; Peroxiredoxin IV; Peroxiredoxin-4; Peroxiredoxin4; PRDX 4; PRDX4; PRDX4_HUMAN; PRX 4; Prx IV; Prx-IV; PRX4; PrxIV; Thioredoxin dependent peroxide reductase A0372; Thioredoxin Peroxidase(Antioxidant Enzyme); Thioredoxin peroxidase; Thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372; TRANK], [PRDX4; PRDX4; PRX-4; AOE372; AOE37-2; HEL-S-97n; AOE37-2; Prx-IV]
Gene, Accession #[PRDX4], Gene ID: 10549, NCBI: Q13162.1, UniProt: Q13162
Catalog #MBS176284
Price$280
Order / More InfoPeroxiredoxin 4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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