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Antigenic Specificity | Human Tubulin Folding Cofactor A |
Clone | [PAT1A5AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: TBCA is a tubulin-folding protein which is involved in the early step of the tubulin folding pathway. TBCA is one of four proteins (cofactors A, D, E, and C) implicated in the pathway directing to properly folded beta-tubulin from folding intermediates. Cofactors A and D are thought to be a factor in capturing and stabilizing beta-tubulin in a quasi-native confirmation. TBCA is crucial for cell viability, if reduced it causes a decrease in the amount of soluble tubulin, alterations in microtubules and G1 cell cycle arrest. Cofactor E attaches to the cofactor D-tubulin complex, afterward, interaction with cofactor C triggers the release of tubulin polypeptides that are committed to the native state. |
Immunogen | Immunogen: Anti-human TBCA mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TBCA amino acids 1-108 purified from E Coli. |
Other Names | [TBCA; Tubulin Folding Cofactor A, Mouse Human; Tubulin-specific chaperone A; Tubulin-folding cofactor A; CFA; TCP1-chaperonin cofactor A; TBCA], [TBCA; TBCA; CFA] |
Gene, Accession # | [TBCA], Gene ID: 6902, NCBI: NP_004598.1 |
Catalog # | MBS140326 |
Price | $140, $205, $505 |
Order / More Info | Human Tubulin Folding Cofactor A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |