SMURF2 (C-term), 702-731 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SMURF2 (C-term), 702-731 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SMURF2 (C-term), 702-731 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, Xenopus) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SMURF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 702-731 amino acids from the C-terminal region of human SMURF2. SMURF2 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein interacts with SMAD1, SMAD2 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. It enhances the inhibitory activity of SMAD7 and reduces the transcriptional activity of SMAD2. Coexpression of SMURF2 with SMAD1 results in considerable decrease in steady-state level of SMAD1 protein and a smaller decrease of SMAD2 level. |
| Immunogen | n/a |
| Other Names | [E3 ubiquitin-protein ligase SMURF2; hSMURF2; 632-; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF2] |
| Gene, Accession # | [SMURF2], Gene ID: 64750, NCBI: NP_073576.1, UniProt: Q9HAU4 |
| Catalog # | MBS9205919 |
| Price | $165, $370 |
| Order / More Info | SMURF2 (C-term), 702-731 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Tajima, Y., et al., J. Biol. Chem. 278(12):10716-10721 (2003). Suzuki, C., et al., J. Biol. Chem. 277(42):39919-39925 (2002). Ebisawa, T., et al., J. Biol. Chem. 276(16):12477-12480 (2001). Zhu, H., et al., Nature 400(6745):687-693 (1999). Lambris, J., et al., J. Immunol. Methods 27(1):55-59 (1979). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies