SHANK3 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SHANK3 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: SH3 and multiple ankyrin repeat domains 3 (SHANK3), a member of the Shank gene family, plays a role in synapse formation and dendritic spine maturation. Shank proteins (Shank 1-3) containing PDZ domains are scaffold proteins of the postsynaptic density (PSD) that connect neurotransmitter receptors and ion channels proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development. Mutations of SHANK3 are a cause of autism spectrum disorder (ASD) and the neurological symptoms of 22q13.3 deletion syndrome. |
| Immunogen | Immunogen: SHANK3 antibody was raised against a 19 amino acid synthetic peptide near the center of human SHANK3. Positive Control: Western Blot:3T3 cell LysateIHC: Human brain tissue |
| Other Names | [SH3 and multiple ankyrin repeat domains 3; ProSAP2; PSAP2; SPANK-2; Proline-rich synapse-associated protein 2], [SHANK3; SHANK3; PSAP2; SCZD15; PROSAP2; SPANK-2; DEL22q13.3; KIAA1650; PROSAP2; PSAP2; Shank3; ProSAP2] |
| Gene, Accession # | [SHANK3], Gene ID: 85358, NCBI: NP_277052.1, UniProt: Q9BYB0 |
| Catalog # | MBS840331 |
| Price | $430 |
| Order / More Info | SHANK3 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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