Human ADAM17 / TACE Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human ADAM17 / TACE |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | Bat, bovine, chicken, gorilla, human, monkey. predicted reactivity: Gibbon, mouse, rat, dog, hamster, horse, porcine, Xenopus (at least 90% immunogen sequence identity) |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 0.5 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human ADAM17. This antibody is expected to recognise isoform 1 (represented by NP_003174) and not isoform 2 (represented by NP_068604). Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. |
| Immunogen | Immunogen Description: Synthetic peptide LQRQNRVDSKETEC from the C-terminus of human ADAM17 (NP_003174.3). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Elephant, Bat, Bovine, Turkey, Sparrow, Chicken, Platypus (100%). |
| Other Names | [ADAM17 / TACE (C-Terminus) IHC-plus; CD156B; CD156b antigen; CSVP; ADAM 17; NISBD; TNF-alpha converting enzyme; TNF-alpha convertase; TNF-alpha-converting enzyme; Snake venom-like protease; TACE; Human ADAM17; TACE], [TACE] |
| Gene, Accession # | [ADAM17], Gene ID: 6868, NCBI: NP_003174.3, UniProt: P78536 |
| Catalog # | MBS247809 |
| Price | $530 |
| Order / More Info | Human ADAM17 / TACE Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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