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Antigenic Specificity | EWSR1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as wel |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EWSR1 |
Other Names | [RNA-binding protein EWS isoform 3; RNA-binding protein EWS; RNA-binding protein EWS; EWS RNA binding protein 1; EWS oncogene; Ewing sarcoma breakpoint region 1 protein] |
Gene, Accession # | [EWSR1], Gene ID: 2130, NCBI: NP_001156757.1, UniProt: Q01844 |
Catalog # | MBS3223459 |
Price | $335 |
Order / More Info | EWSR1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |