Edit |   |
---|---|
Antigenic Specificity | (Mouse) Rnf2 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This mouse Rnf2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the Central region of mouse Rnf2. E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, thro |
Immunogen | n/a |
Other Names | [E3 ubiquitin-protein ligase RING2; 632-; RING finger protein 1B; RING1b; RING finger protein 2; Rnf2; DinG; Ring1b] |
Gene, Accession # | [Rnf2], Gene ID: 19821, NCBI: NP_035407.1, UniProt: Q9CQJ4 |
Catalog # | MBS9215216 |
Price | $165, $370 |
Order / More Info | (Mouse) Rnf2 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Schoorlemmer J.,et al.EMBO J. 16:5930-5942(1997). Carninci P.,et al.Science 309:1559-1563(2005). Ebert L.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Garcia E.,et al.EMBO J. 18:3404-3418(1999). Suzuki M.,et al.Development 129:4171-4183(2002). |