casp9 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-casp9 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | casp9 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family (1,2). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Another cleavage occurs at Asp330 producing a p37 subunit that can serve to amplify the apoptotic response (3-6). Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to initiate a caspase cascade, which leads to apoptosis (7-10). |
| Immunogen | Immunogen: A Fusion protein of human casp9 |
| Other Names | [CASP9 Rabbit pab], [casp9; APAF 3; APAF3; MCH6; Caspase 9; Apoptotic protease Mch 6] |
| Gene, Accession # | [casp9], Gene ID: 842, NCBI: NP_001220.2, UniProt: P55211 |
| Catalog # | MBS125686 |
| Price | $200, $275, $430 |
| Order / More Info | casp9 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Duan, H. et al. (1996) J. Biol. Chem. 271, 16720-16724. 2. Srinivasula, S. M. et al. (1996) J. Biol. Chem. 271, 27099-27106. 3. Liu, X. et al. (1996) Cell 86, 147-157. 4. Li, P. et al. (1997) Cell 91, 479-489. 5. Zou, H. et al. (1999) J. Biol. Chem. 274, 11549-11556. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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