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Antigenic Specificity | CD68 |
Clone | [6F3] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The CD68 antibody detects endogenous CD68 proteins. The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. |
Immunogen | n/a |
Other Names | [CD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; macrophage antigen CD68] |
Gene, Accession # | [CD68], Gene ID: 968, NCBI: NP_001035148.1, UniProt: P34810 |
Catalog # | MBS9400204 |
Price | $200, $255 |
Order / More Info | CD68 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |