Edit |   |
---|---|
Antigenic Specificity | E-Cadherin |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, rat, mouse, dog, and monkey. |
Isotype | n/a |
Format | unconjugated |
Size | 0.4 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects endogenous levels of total E-cadherin protein by Western blot in the whole cell lysates (COS-7 and MDCK). E-Cadherin. Goat polyclonal to CDH1. CDH1 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one transmembrane domain, and a and a highly conserved intracellular domain that binds b-catenin and p120-catenin. CDH1 is involved in mechanisms regulating proliferation, mobility and cell-cell adhesions of epithelial cells. Loss of E-cadherin function or expression has been implicated in cancer metastasis and progression. |
Immunogen | Immunogen: Recombinant peptide derived from within residues 750 to 850 of human CDH1 produced in E. coli. |
Other Names | [CDH1; ARC-1; CAM 120/80; CD324; CDH1; cdhc-A; CDHE; ECAD; E-Cad E-cadherin; Epithelial cadherin; l-cam; LCAM; P09803; P12830 / Q9R0T4; UVO; Uvomorulin; XBcad; XB-cadherin; XTCAD-1], [CDH1; CDH1; UVO; CDHE; ECAD; LCAM; Arc-1; CD324; CDHE; UVO; E-cadherin] |
Gene, Accession # | [CDH1], Gene ID: 999, NCBI: AAI46663.1, UniProt: P12830 |
Catalog # | MBS448004 |
Price | $285 |
Order / More Info | E-Cadherin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |