Mouse CD273 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD273
Clone[TY25]
Host SpeciesRat
Reactive Speciesn/a
IsotypeIgG2a
Formatunconjugated
Size0.25 mg
ConcentrationIgG concentration 1.0 mg/ml
ApplicationsImmunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP)
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DescriptionRat anti Mouse CD273 antibody, clone TY25 recognises mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor (Matsumoto et al.). Removal of Sodium Azide is recommended prior to use in f
Immunogenn/a
Other Names[programmed cell death 1 ligand 2; Programmed cell death 1 ligand 2; programmed cell death 1 ligand 2; PD-1 ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; butyrophilin-like protein; programmed death ligand 2; programmed cell death 1 ligand 2; Butyrophilin B7-DC; B7-DC; CD_antigen: CD273], [Pdcd1lg2; Pdcd1lg2; Btdc; B7-DC; PD-L2; F730015O22Rik; B7dc; Btdc; Cd273; Pdl2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC]
Gene, Accession #[CD273], Gene ID: 58205, NCBI: NP_067371.1, UniProt: Q9WUL5
Catalog #MBS214323
Price$430
Order / More InfoMouse CD273 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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