Human Tumor necrosis factor ligand superfamily member 18 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Tumor necrosis factor ligand superfamily member 18
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionCytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
ImmunogenImmunogen: Recombinant human Tumor necrosis factor ligand superfamily member 18 protein (72-199aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5764 / sc-5762 / sc-66906
Other Names[Activation-inducible TNF-related ligand; AITRL; Glucocorticoid-induced TNF-related ligand; hGITRL; TNFSF18; AITRL; GITRL; TL6; UNQ149/PRO175], [TNFSF18; TNFSF18; TL6; AITRL; GITRL; TNLG2A; hGITRL; AITRL; GITRL; TL6; AITRL; hGITRL]
Gene, Accession #[TNFSF18], Gene ID: 8995, NCBI: NP_005083.2, UniProt: Q9UNG2
Catalog #MBS1493138
Price$120, $160
Order / More InfoHuman Tumor necrosis factor ligand superfamily member 18 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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