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Antigenic Specificity | Bnip3L (IN) (nix) (bcl 2 family) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3, and Nix (for Nip3-like protein X) (1-3). Bnip3L/Bnip3 /Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis (2,3). Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria. The messenger RNA of Bnip3L is ubiquitously expressed in huma |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 77 to 92 of the human Bnip3L protein. Immunogen sequence is identical in the mouse protein. |
Other Names | [BNIP3A; BNIP3H; NIX], [BNIP3L; BNIP3L; NIX; BNIP3a; BNIP3A; BNIP3H; NIX; NIP3L] |
Gene, Accession # | [Bnip3L], Gene ID: 665, NCBI: NP_004322.1, UniProt: O60238 |
Catalog # | MBS396006 |
Price | $510 |
Order / More Info | Bnip3L (IN) (nix) (bcl 2 family) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |