Edit |   |
---|---|
Antigenic Specificity | HAVCR2 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HAVCR2 Antibody detects endogenous levels of total HAVCR2. The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto-and alloimmune responses, and promotes immunological tolerance. |
Immunogen | Immunogen: Recombinant protein of human HAVCR2 |
Other Names | [TIM3; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2] |
Gene, Accession # | [HAVCR2], Gene ID: 84868, NCBI: NP_116171.3, UniProt: Q8TDQ0 |
Catalog # | MBS8516449 |
Price | $290 |
Order / More Info | HAVCR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |