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Antigenic Specificity | Histone H2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Histone H2B protein. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Albig W., Genomics 40:314-322(1997).Marzluff W.F., Genomics 80:487-498(2002).Mungall A.J., Nature 425:805-811(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human Histone H2B. |
Other Names | [Histone H2B type 1-H; H2B.j; H2B/j; HIST1H2BH; H2BFJ] |
Gene, Accession # | Gene ID: 8345, NCBI: NP_003515.1, UniProt: Q93079 |
Catalog # | MBS9407790 |
Price | $200, $255 |
Order / More Info | Histone H2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |