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Antigenic Specificity | ATR (Phospho Ser428) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-ATR (S428) Polyclonal Antibody detects endogenous levels of ATR protein only when phosphorylated at S428. The protein encoded by ATR (ATR serine/threonine kinase) belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of ATR are associated with Seckel syndrome. An alternatively spliced transcript va |
Immunogen | Immunogen: Synthesized peptide derived from human ATR around the phosphorylation site of S428 |
Other Names | [Rabbit ATR (phospho Ser428); ATR; FRP1; Serine/threonine-protein kinase ATR; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1] |
Gene, Accession # | [ATR], Gene ID: 545, NCBI: NP_001175.2, UniProt: Q13535 |
Catalog # | MBS9706288 |
Price | $130, $220, $325 |
Order / More Info | ATR (Phospho Ser428) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |