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Antigenic Specificity | STEAP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This STEAP1 antibody does not cross-react with other STEAP proteins. STEAP1 Antibody: The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. The normal function of STEAP is still uncertain; unlike other members of the STEAP family, STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity. However, its expression is highly increased in multiple cancer cell lines, including prostate, bladder, colon, and ovarian cancers. Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors, enabling them to recognize STEAP1-pos |
Immunogen | Immunogen: STEAP1 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human STEAP1. Buffer: STEAP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [STEAP1; STEAP; PRSS24; STEAP; Metalloreductase STEAP1; Six-transmembrane epithelial antigen of prostate 1; six transmembrane epithelial antigen of the prostate 1], [STEAP1; PRSS24; STEAP] |
Gene, Accession # | [STEAP1], Gene ID: 392745, NCBI: EAL24166, UniProt: Q9UHE8 |
Catalog # | MBS150284 |
Price | $375 |
Order / More Info | STEAP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |