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Antigenic Specificity | Human CD44 |
Clone | [3C7] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1,k |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reactive with recombinant and native human CD44. CD44, a well-known cancer stem cell (CSC) marker and adhesion molecule, is involved in the complex process of epithelial-mesenchymal transition (EMT). It is a glycoprotein receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44, especially its variant CD44v, is implicated in driving tumor growth, metastasis, and relapse following therapy in a wide variety of human cancers such as breast and ovarian cancers. |
Immunogen | Immunogen: Recombinant human CD44 produced by mammalian expression system. The target gene encoding Gln21-Pro220 is expressed with a 6His tag at the C-terminus. Accession #:P16070. Light Chain: Kappa. Fusion Myeloma: Sp2/0-Ag14. Target Protein: Human CD44 |
Other Names | [mAb Human CD48; Mouse to human CD44, Clone 3C7; Mouse (mAb) to human cluster of differentiation 44 (CD44); Mouse (mAb) to human CD44], [CD44; CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I] |
Gene, Accession # | [CD44], Gene ID: 960, NCBI: AAB30429.1 |
Catalog # | MBS590090 |
Price | $490 |
Order / More Info | Human CD44 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |