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Antigenic Specificity | ST5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Suppression of tumorigenicity 5 protein(ST5) detection. Tested with WB in Human, Mouse, Rat. Background: Suppression of tumorigenicity 5 is a protein that in humans is encoded by the ST5 gene. This gene is mapped to 11p15.4. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ST5 (571-586aa KRHSHDDMLLLAQLSL), different from the related mouse and rat sequences by one amino acid. |
Other Names | [Suppression of tumorigenicity 5 protein; suppression of tumorigenicity 5; DENN domain containing protein 2B; DENN domain-containing protein 2B; DENN/MADD domain containing 2B; DENND2B; HeLa tumor suppression 1; HTS1; p126; ST 5; ST5; Suppression of tumorigenicity 5; Suppression of tumorigenicity 5 protein], [ST5; ST5; HTS1; p126; DENND2B; DENND2B; HTS1] |
Gene, Accession # | [ST5], Gene ID: 6764, NCBI: P78524.3, UniProt: P78524 |
Catalog # | MBS176943 |
Price | $280 |
Order / More Info | ST5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |