Mouse CD72.1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD72.1
Clone[10-1.D.2]
Host SpeciesMouse
Reactive Speciesmouse
IsotypeIgG2b kappa
Formatunconjugated
Size0.5 mg
Concentrationn/a
ApplicationsFlow Cytometry
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DescriptionSpecificity: Mouse CD72.1/Lyb-2.1, 45 kDa. Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells.^1,2 The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing.^1 However, 10-1.D.2 can itself trigger a positive signal by binding CD72.^1-5.
ImmunogenImmunogen: DBA/2 mouse spleen cells
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS673439
Price$320
Order / More InfoMouse CD72.1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Luo, W., H Van de Velde, I. von Hoegen, J.R. Parnes, and K. Thielemans. 1992. J. Immunol. 148:1630.2. Subbarao, B., and D.E. Mosier. 1983. J. Immunol. 130:2033.3. Snow, E.C., J.J. Mond, and B. Subbarao. 1986. J. Immunol. 137:1793.4. Robinson, W.H., M.M Landolfi, H. Schaffer and J.R. Parnes. 1993. J. Immunol. 151:4764.5. Beavil, A.J., R.L. Edmeades, H.J. Gould and B.J. Sutton. 1992. Proc. Nat. Acad. Sci. 89:753.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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