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Antigenic Specificity | Mouse CD72.1 |
Clone | [10-1.D.2] |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2b kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mouse CD72.1/Lyb-2.1, 45 kDa. Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells.^1,2 The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing.^1 However, 10-1.D.2 can itself trigger a positive signal by binding CD72.^1-5. |
Immunogen | Immunogen: DBA/2 mouse spleen cells |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS673439 |
Price | $320 |
Order / More Info | Mouse CD72.1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Luo, W., H Van de Velde, I. von Hoegen, J.R. Parnes, and K. Thielemans. 1992. J. Immunol. 148:1630.2. Subbarao, B., and D.E. Mosier. 1983. J. Immunol. 130:2033.3. Snow, E.C., J.J. Mond, and B. Subbarao. 1986. J. Immunol. 137:1793.4. Robinson, W.H., M.M Landolfi, H. Schaffer and J.R. Parnes. 1993. J. Immunol. 151:4764.5. Beavil, A.J., R.L. Edmeades, H.J. Gould and B.J. Sutton. 1992. Proc. Nat. Acad. Sci. 89:753. |