NRG1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNRG1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionRabbit polyclonal to NRG1. Heregulin (HRG), also called neuregulin (NRG1), neu differentiation factor (NDF) or glial growth factor-2 (GGF-2), is a soluble growth factor synthesized as a transmembrane precursor molecule. Metalloproteinases and other proteases catalyze the cleavage of its extracellular domain which is then released and functions as a ligand for ErbB3 and ErbB4 receptor tyrosine kinase. The signaling pathways of HRG-ErbB3/ErbB4 are involved in regulation of cell proliferation, differentiation, invasion, and survival of both normal and malignant tissues (1,2). Abnormality of HRG-ErbB signaling leads to development of a variety of human diseases.HRG family has four isoforms including HRG-1, -2, -3 and -4, which are derived from
ImmunogenImmunogen: A synthetic -peptide of human NRG1
Other Names[NRG1; Heregulin NRG1; Heregulin NRG1; NRG1; ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; NDF; SMDF;], [NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG]
Gene, Accession #Gene ID: 3084, NCBI: NP_001153467.1, UniProt: Q02297
Catalog #MBS125466
Price$275, $430
Order / More InfoNRG1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Breuleux, M. (2007) Cell Mol Life Sci 64, 2358-77. 2. Ozaki, M. et al. (2004) J Neurochem 91, 176-88. 3. Falls, D.L. (2003) Exp Cell Res 284, 14-30.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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