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Antigenic Specificity | NRG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to NRG1. Heregulin (HRG), also called neuregulin (NRG1), neu differentiation factor (NDF) or glial growth factor-2 (GGF-2), is a soluble growth factor synthesized as a transmembrane precursor molecule. Metalloproteinases and other proteases catalyze the cleavage of its extracellular domain which is then released and functions as a ligand for ErbB3 and ErbB4 receptor tyrosine kinase. The signaling pathways of HRG-ErbB3/ErbB4 are involved in regulation of cell proliferation, differentiation, invasion, and survival of both normal and malignant tissues (1,2). Abnormality of HRG-ErbB signaling leads to development of a variety of human diseases.HRG family has four isoforms including HRG-1, -2, -3 and -4, which are derived from |
Immunogen | Immunogen: A synthetic -peptide of human NRG1 |
Other Names | [NRG1; Heregulin NRG1; Heregulin NRG1; NRG1; ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; NDF; SMDF;], [NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG] |
Gene, Accession # | Gene ID: 3084, NCBI: NP_001153467.1, UniProt: Q02297 |
Catalog # | MBS125466 |
Price | $275, $430 |
Order / More Info | NRG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Breuleux, M. (2007) Cell Mol Life Sci 64, 2358-77. 2. Ozaki, M. et al. (2004) J Neurochem 91, 176-88. 3. Falls, D.L. (2003) Exp Cell Res 284, 14-30. |