RPS6KA3 (S369) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RPS6KA3 (S369) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mousepredicted: zebrafish |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 342-376 amino acids from human. Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1 and histone H3 at 'Ser-10', which results in the subsequent transcriptional activation of several immediate-early genes. |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 2.7.11.1; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; Ribosomal S6 kinase 2; RSK-2; pp90RSK2; RPS6KA3; ISPK1; MAPKAPK1B; RSK2] |
| Gene, Accession # | [RPS6KA3], Gene ID: 6197, NCBI: NP_004577.1, UniProt: P51812 |
| Catalog # | MBS9231234 |
| Price | $165, $370 |
| Order / More Info | RPS6KA3 (S369) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bjoerbaek C.,et al.Diabetes 44:90-97(1995). Ota T.,et al.Nat. Genet. 36:40-45(2004). Totoki Y.,et al. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. Ross M.T.,et al.Nature 434:325-337(2005). Moller D.E.,et al.Am. J. Physiol. 266:C351-C359(1994). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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