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Antigenic Specificity | RNF41 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88. Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus (By similarity). Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hematopoietic progenitor cell differentiation into myeloerythroid lineages (By similarity). Contributes to the maintenance of steady-state ERBB3 levels by mediating its growth factor-independent deg |
Immunogen | Immunogen: Recombinant human E3 ubiquitin-protein ligase NRDP1 protein (1-317AA) |
Other Names | [E3 ubiquitin-protein ligase NRDP1; RING finger protein 41; RNF41; FLRF; NRDP1; SBBI03] |
Gene, Accession # | [RNF41], Gene ID: 10193, NCBI: NP_001229755.1, UniProt: Q9H4P4 |
Catalog # | MBS7046247 |
Price | $120, $160 |
Order / More Info | RNF41 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |