Lamin A and C Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Lamin A and C antibody, protein, ELISA kits.
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| Antigenic Specificity | Lamin A and C |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | Cattle, dog, hamster, human, mouse, rat, sheep |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 1 mL |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: 131C3 reacts with an epitope located between residues 319-566 in lamin A and C. Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with cond |
| Immunogen | Source Note: 131C3 is a mouse monoclonal IgG1/k antibody derived by fusion of P3/X63.Ag8.653 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with purified rat liver lamins. |
| Other Names | [Prelamin-A/C; Prelamin-A/C; lamin; lamin A/C; Lamin-A/CAlternative name(s):70 kDa lamin; Renal carcinoma antigen NY-REN-32], [LMNA; LMNA; FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; MADA; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B; LMN1] |
| Gene, Accession # | Gene ID: 4000, NCBI: P02545.1, UniProt: P02545 |
| Catalog # | MBS570441 |
| Price | $510 |
| Order / More Info | Lamin A and C Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Pugh, G. E., Coates, P. J., Lane, E. B., Raymond, Y., and Quinlan, R. A. (1997). Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells, J Cell Sci 110:2483-93. 2. Neri, L. M., Raymond, Y., Giordano, A., Borgatti, P., Marchisio, M., Capitani, S., and Martelli, A. M. (1999). Spatial distribution of lamin A and B1 in the K562 cell nuclear matrix stabilized with metal ions, J Cell Biochem 75:36-45. 3. Neri, L. M., Raymond, Y., Giordano, A., Capitani, S., and Martelli, A. M. (1999). Lamin A is part of the internal nucleoskeleton of Human erythroleukemia cells, J Cell Physiol 178:284-95. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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