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Antigenic Specificity | IL11 (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IL11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-61 amino acids from human IL11. Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. |
Immunogen | n/a |
Other Names | [Interleukin-11; IL-11; Adipogenesis inhibitory factor; AGIF; Oprelvekin; IL11] |
Gene, Accession # | [IL11], Gene ID: 3589, NCBI: NP_000632.1, UniProt: P20809 |
Catalog # | MBS9231067 |
Price | $165, $370 |
Order / More Info | IL11 (N-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Paul S.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:7512-7516 (1990). Kawashima I.,et al.FEBS Lett. 283:199-202 (1991). McKinley D.,et al.Genomics 13:814-819 (1992). Ota T.,et al.Nat. Genet. 36:40-45 (2004). Grimwood J.,et al.Nature 428:529-535 (2004). |