SCF Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SCF |
| Clone | [four helix cytokine core] |
| Host Species | Mouse |
| Reactive Species | human, rat |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.5 mg, 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SCF is a stromal cell- derived cytokine synthesized by fibroblasts and other cell types. SCF promotes proliferation and early differentiation of cells at the level of multipotential stem cells. It has been suggested that SCF is essential for optimal production of various hematopoietic lineages, mainly because of its ability to prevent apoptosis when it co- stimulates with other cytokines. The receptor for SCF, designated SCFR (CD117), is the oncogene designated as KIT. The biological activities of SCF are synergised considerably by colony stimulating factors GM-CSF and G-CSF, and also by IL7, Epo and some other growth and differentiation factors. In combination with IL7 SCF stimulates the proliferation of pre-B-cells. SCF is also a potent c |
| Immunogen | Host Note: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with recombinant E. coli-derived Human SCF. |
| Other Names | [Mouse Human SCF; Kitlg; scf; stem cell factor; kit ligand;; mab], [KITLG; MGF; SCF; MGF; SCF; sKITLG] |
| Gene, Accession # | [SCF], Gene ID: 4254, NCBI: NP_000890.1, UniProt: P21583 |
| Catalog # | MBS550034 |
| Price | $550, $855 |
| Order / More Info | SCF Antibody from MYBIOSOURCE INC. |
| Product Specific References | • pollen-specific skp1-like proteins are components of functional SCF complexes and essential for lily pollen tube elongation.Plant Cell Physiol., Aug 2009; 50: 1558 - 1572. • SCF induces -globin gene expression by regulating downstream transcription factor coup-tfii.Blood, Jul 2009; 114: 187 - 194. • jfk, a kelch domain-containing f-box protein, links the SCF complex to p53 regulation.PNAS, Jun 2009; 106: 10195 - 10200. • the extracellular signal-regulated kinase-mitogen-activated protein kinase pathway phosphorylates and targets cdc25a for SCFβ-trcp-dependent degradation for cell cycle arrest.Mol. Biol. Cell, Apr 2009; 20: 2186 - 2195. • mmp9 and SCF protect from apoptosis in acute kidney injury.J. Am. Soc. Nephrol., Apr 2009; 20: 787 - 797. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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