Human Protein-arginine deiminase type-4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Protein-arginine deiminase type-4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. Citrullinates histone H1 at 'Arg-54' (to form H1R54ci), histone H3 at 'Arg-2', 'Arg-8', 'Arg-17' and/or 'Arg-26' (to form H3R2ci, H3R8ci, H3R17ci, H3R26ci, respectively) and histone H4 at 'Arg-3' (to form H4R3ci). Acts as a key regulator of stem cell maintenance by mediating citrullination of histone H1: citrullination of 'Arg-54' of histone H1 (H1R54ci) results in H1 displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance. Promotes profound chromatin decondensation during the innate immune response to |
| Immunogen | Immunogen: Recombinant human Protein-arginine deiminase type-4 protein(1-250aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47287 / sc-98991 |
| Other Names | [HL-60 PAD; Peptidylarginine deiminase IV; Protein-arginine deiminase type IV; PADI4; PADI5; PDI5], [PADI4; PADI4; PAD; PAD4; PDI4; PDI5; PADI5; PAD4; PADI5; PDI5] |
| Gene, Accession # | [PADI4], Gene ID: 23569, NCBI: NP_036519.2, UniProt: Q9UM07 |
| Catalog # | MBS1492858 |
| Price | $120, $160 |
| Order / More Info | Human Protein-arginine deiminase type-4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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