Mouse CD49b/VLA-2a Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD49b/VLA-2a |
| Clone | [DX5] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgM kappa |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Mouse CD49b, Mr 160-kDa. The monoclonal antibody DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and alpha 2 integrin.1 The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J, DBA/1, DBA/2, SJL, SWR).2. 3 Three-color flow cytometry analysis has revealed that most cells that express NK-1.1 (NKR-P1C) also express CD49b. However, small subsets of DX5+NK-1.1- and DX5-NK- 1.1+ cells can be found, especially among the CD3+ population of T lymphocytes.2 NK cells cultured in the presence of IL-2 progressively lose reactivity with DX5 as a consequence of cellular proliferation.1 Therefore |
| Immunogen | Immunogen: RIL-2-propagated NK1.1^+ cells from C57BL/6 mice. Fusion Partner: Mouse SP2/0 myeloma cell line |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS673567 |
| Price | $280 |
| Order / More Info | Mouse CD49b/VLA-2a Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Arase, H., T. Saito, J.H. Phillips, and L.L. Lanier. 2001. J. Immunol. 167:1141-1144.2. Abrams, J. Personal communication3. Moore, T.A., U. von Freeden-Jeffry, R. Muray, and A. Zlotnik. 1996. J. Immunol. 157:2366-2373.4. Lazetic, S. and J.H. Phillips. Unpublished observations. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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