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Antigenic Specificity | LCK - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against LCK. It was validated on Western BlotTarget Description: LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LCK |
Other Names | [tyrosine-protein kinase Lck isoform a; Tyrosine-protein kinase Lck; tyrosine-protein kinase Lck; LCK proto-oncogene, Src family tyrosine kinase; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK] |
Gene, Accession # | [LCK], Gene ID: 3932, NCBI: NP_001036236.1, UniProt: P06239 |
Catalog # | MBS3211717 |
Price | $335 |
Order / More Info | LCK - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |