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Antigenic Specificity | MNDA (N-term), 26-53 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.26 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MNDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of human MNDA. The myeloid cell nuclear differentiation antigen (MNDA) isdetected only in nuclei of cells of the granulocyte-monocytelineage. A 200-amino acid region of human MNDA is strikinglysimilar to a region in the proteins encoded by a family ofinterferon-inducible mouse genes, designated Ifi-201, Ifi-202, andIfi-203, that are not regulated in a cell- or tissue-specificfashion. The 1.8-kb MNDA mRNA, which contains aninterferon-stimulated response element in the 5-prime untranslatedregion, was significantly upregulated in human monocytes exposed tointerfe |
Immunogen | n/a |
Other Names | [Myeloid cell nuclear differentiation antigen; MNDA] |
Gene, Accession # | [MNDA], Gene ID: 4332, NCBI: NP_002423.1, UniProt: P41218 |
Catalog # | MBS9207672 |
Price | $165, $370 |
Order / More Info | MNDA (N-term), 26-53 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kimkong, I., et al. J. Rheumatol. 37(7):1544-1547(2010) Kanellis, G., et al. Leukemia 23(10):1847-1857(2009) Joshi, A.D., et al. Clin. Cancer Res. 13 (18 PT 1), 5295-5304 (2007) : Briggs, R.C., et al. Cancer Res. 66(9):4645-4651(2006) Asefa, B., et al. FEBS Lett. 580(5):1205-1214(2006) |