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Antigenic Specificity | HDAC11 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Histone deacetylase 11(HDAC11) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Histone deacetylase 11 is a 39kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11 (47-81aa NFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLN), different from the related mouse sequence by one amino acid. Ig Type: Rabbit IgG |
Other Names | [Histone deacetylase 11; FLJ22237; HD 11; HD11; HDA11_HUMAN; HDAC 11; HDAC11; Histone deacetylase 11; histone deacetylase 11], [HDAC11; HDAC11; HD11; HD11] |
Gene, Accession # | [HDAC11], Gene ID: 79885, NCBI: NP_001129513.1, UniProt: Q96DB2 |
Catalog # | MBS177658 |
Price | $315 |
Order / More Info | HDAC11 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: HDAC11 histone deacetylase 11. 2. Gao L, Cueto MA, Asselbergs F, Atadja P (Jul 2002). Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family.The Journal of Biological Chemistry 277(28): 25748-55. |