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Antigenic Specificity | WSB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: WSB1 antibody is human specific. The WD repeat and SOCS box-containing 1 (WSB1, also known as SWIP1), is a member of the WD-protein subfamily (1). It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus and expressed as multiple alternatively spliced isoforms (1,2). WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2 (3). Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis (4,5). |
Immunogen | Immunogen: WSB1 antibody was raised against a 16 amino acid peptide near the amino terminus of human WSB1. Buffer: WSB1 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [WD repeat and SOCS box containing 1; SOCS box-containing WD protein SWiP-1; SWIP1; WD repeat and SOCS box-containing protein 1; WSB-1; WD repeat and SOCS box containing 1], [WSB1; WSB1; SWIP1; WSB-1; SWIP1; WSB-1] |
Gene, Accession # | [WSB1], Gene ID: 26118, NCBI: NP_056441, UniProt: Q9Y6I7 |
Catalog # | MBS153552 |
Price | $375 |
Order / More Info | WSB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |