WSB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWSB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: WSB1 antibody is human specific. The WD repeat and SOCS box-containing 1 (WSB1, also known as SWIP1), is a member of the WD-protein subfamily (1). It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus and expressed as multiple alternatively spliced isoforms (1,2). WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2 (3). Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis (4,5).
ImmunogenImmunogen: WSB1 antibody was raised against a 16 amino acid peptide near the amino terminus of human WSB1. Buffer: WSB1 antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[WD repeat and SOCS box containing 1; SOCS box-containing WD protein SWiP-1; SWIP1; WD repeat and SOCS box-containing protein 1; WSB-1; WD repeat and SOCS box containing 1], [WSB1; WSB1; SWIP1; WSB-1; SWIP1; WSB-1]
Gene, Accession #[WSB1], Gene ID: 26118, NCBI: NP_056441, UniProt: Q9Y6I7
Catalog #MBS153552
Price$375
Order / More InfoWSB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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