Protein Tyrosine Phosphatase, non-receptor type 6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Protein Tyrosine Phosphatase, non-receptor type 6 |
| Clone | [CPTC-PTPN6-2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PTPN6, which is also designated as SHP-1, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating intracellular signaling for various molecules. In T-cell lymphomas and other malignancies, SHP-1 phosphatase expression is lost, by a thus far undetermined mechanism. Preliminary studies suggest that it may be helpful in differentiating mantle/marginal zone lymphomas (SHP-1+) from follicular lymphomas (SHP-1 negative). |
| Immunogen | Immunogen: Recombinant human full-length PTPN6 protein |
| Other Names | [PTPN6; SHP1; protein tyrosine phosphatase; non-receptor type 6; HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; 70 kda SHP-1L protein; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; protein-tyrosine phosphatase 1C; PTPN6/SHP] |
| Gene, Accession # | [PTPN6], Gene ID: 5777, NCBI: NP_002822.2, UniProt: P29350 |
| Catalog # | MBS4381211 |
| Price | $190, $340, $340 |
| Order / More Info | Protein Tyrosine Phosphatase, non-receptor type 6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kossev, P M, et al. The American Journal of Surgical Pathology, July 2001. 2. Zhang, Q., et al. Proc. Natl. Acad. Sci. U.S.A. (2005) |
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MYBIOSOURCE INC.
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