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Antigenic Specificity | Peroxiredoxin 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Thioredoxin-dependent peroxide reductase, mitochondrial(PRDX3) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: PRDX3(peroxiredoxin 3) also known as AOP-1, MER5, SP-22 or PRX3, is localized exclusively in mitochondria. The deduced 256-amino acid human AOP1 protein shares 86% amino acid sequence similarity with mouse Aop1, and significant similarity with both the human proliferation-associated gene A product and the mouse stress-induced peritoneal macrophage protein Msp23. The PRDX3 gene is mapped on 10q26.11. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Peroxiredoxin 3 (240-257aa TIKPSPTASKEYFEKVHQ), identical to the related rat sequence, and different from the related human sequence by three amino acids. |
Other Names | [Thioredoxin-dependent peroxide reductase, mitochondrial; peroxiredoxin 3; Antioxidant Protein 1; AOP 1; AOP-1; AOP1; HBC189; MER 5; MER5; MGC104387; MGC24293; mitochondrial; Mitochondrial thioredoxin dependent peroxide reductase; peroxiredoxin 3; PeroxiredoxinIII; Peroxiredoxin-3; Peroxiredoxin3; PRDX 3; PRDX3; PRDX3_HUMAN; PRO1748; Protein MER5 homolog; PRX III; PRXIII; Prx-III; PRX3; SP 22; SP-22; SP22; Thioredoxin dependent peroxide reductase mitochondrial; Thioredoxin dependent peroxide reductase precursor; Thioredoxin-dependent peroxide reductase], [Prdx3; Prdx3; Aop1; Ef2l; Mer5; Prx3; SP22; TDXM; D0Tohi1; AW822249; Aop1; Mer5; AOP-1] |
Gene, Accession # | [PRDX3], Gene ID: 11757, NCBI: P20108.1, UniProt: P20108 |
Catalog # | MBS176305 |
Price | $315 |
Order / More Info | Peroxiredoxin 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |