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Antigenic Specificity | WISP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: WISP1 antibody detects endogenous levels of WISP1. Function: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.Similarity: Belongs to the CCN family. |
Immunogen | Immunogen: A synthesized peptide derived from human WISP1. Subcellular Location: Secreted Tissue Specificity: Expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Isoform 2 is expressed predominantly in scirrhous gastric carcinoma and, weakly in placenta. Overexpression is associated with several cancers including breast cancer and colon tumors. Isoform 2 is overexpressed in scirrhous gastric carcinoma. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (10 |
Other Names | [CCN 4; CCN family member 4; CCN4; WISP 1; WISP 1c; WISP 1i; WISP 1tc; WISP1c; WISP1i; WISP1tc; WNT 1 induced secreted protein 1; Wnt 1 induced secreted protein; WNT 1 inducible signaling pathway protein 1; Wnt 1 signaling pathway protein 1; Wnt-1 inducible signaling pathway protein 1; WNT1 induced secreted protein 1; Wnt1 induced secreted protein; WNT1 inducible signaling pathway protein 1; Wnt1 signaling pathway protein 1; WNT1-inducible-signaling pathway protein 1] |
Gene, Accession # | [WISP1], Gene ID: 8840, NCBI: NP_001191798.1, UniProt: O95388 |
Catalog # | MBS9603731 |
Price | $240, $280 |
Order / More Info | WISP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |