Bag1 Picoband Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBag1 Picoband
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
ConcentrationAdd 0.2ml of distilled water will yield a concentration of 500ug/ml.
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionDescription: BAG family molecular chaperone regulator 1 (BAG1) is a protein that in humans is encoded by the BAG1 gene. Human BAG1 is mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The Bag1 protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.Protein Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptoti
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Bag1 (323-345aa DTVEQNICQETERLQSTNFALAE), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids. Subcellular Localization: Isoform 1: Nucleus. Cytoplasm. Isoform 1 localizes predominantly to the nucleus. Tissue Specificity: Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout most tissues, except the liver, col
Other Names[BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-associated athanogene 1; BAG1; HAP]
Gene, Accession #[Bag1], Gene ID: 573, NCBI: NP_001165886.1, UniProt: Q99933
Catalog #MBS1750768
Price$315
Order / More InfoBag1 Picoband Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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