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Antigenic Specificity | MMP-12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration thromugh the epidermal and vascular basement membranes in inflammatory disorders. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 460 of human MMP-12 |
Other Names | [MMP12; MMP-12; MMP 12; matrix metalloproteinases 12; matrix metalloproteinases -12; matrix metalloproteinases 12], [MMP12; MMP12; ME; HME; MME; MMP-12; HME; MME; ME; hME; MMP-12] |
Gene, Accession # | [MMP-12], Gene ID: 4321, NCBI: NP_002417 |
Catalog # | MBS840253 |
Price | $150, $290 |
Order / More Info | MMP-12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |