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Antigenic Specificity | Human Protein LYRIC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance. |
Immunogen | Immunogen: Recombinant human Protein LYRIC protein (1-260aa) |
Other Names | [3D3/LYRIC; Astrocyte elevated gene-1 protein; AEG-1; Lysine-rich CEACAM1 co-isolated protein; Metadherin; Metastasis adhesion protein; MTDH; AEG1; LYRIC], [MTDH; MTDH; 3D3; AEG1; AEG-1; LYRIC; LYRIC/3D3; AEG1; LYRIC; AEG-1] |
Gene, Accession # | [MTDH], Gene ID: 92140, NCBI: NP_848927.2, UniProt: Q86UE4 |
Catalog # | MBS1495120 |
Price | $120, $160 |
Order / More Info | Human Protein LYRIC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |