tbx21 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | tbx21 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: tbx21 antibody detects endogenous levels of total tbx21. Function: Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repressing the opposing Th2 and Th17 genetic programs (PubMed:10761931). Activates transcription of a set of genes important for Th1 cell function, including those encoding IFN-gamma and the chemokine receptor CXCR3. Activates IFNG and CXCR3 genes in part by recruiting chromatin remodeling complexes including KDM6B, a SMARCA4-containing SWI/SNF-complex, and an H3K4me2-methyltransferase complex to their promoters and all of these complexes serve to establish a more permissive chromatin state conducive with tran |
| Immunogen | Immunogen: A synthesized peptide derived from human tbx21 Subcellular Location: Nucleus. Tissue Specificity: T-cell specific. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (91%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [T bet; T box 21; T box expressed in T cells; T box protein 21; T box transcription factor TBX21; T cell specific T box transcription factor; T cell specific T box transcription factor T bet; T PET; T-box protein 21; T-box transcription factor TBX21; T-cell-specific T-box transcription factor T-bet; TBET; TBLYM; TBX 21; Tbx21; TBX21_HUMAN; TPET; Transcription factor TBLYM] |
| Gene, Accession # | [tbx21], Gene ID: 30009, NCBI: NP_037483.1, UniProt: Q9UL17 |
| Catalog # | MBS9608336 |
| Price | $240, $280 |
| Order / More Info | tbx21 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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