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Antigenic Specificity | APRIL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of APRIL. The protein encoded by TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of TNFSF13 have been identified; such read-through transcripts are contained in GeneID 407 |
Immunogen | Immunogen: Synthesized peptide derived from part region of human APRIL protein at amino acid sequence of 91-140 |
Other Names | [Rabbit APRIL; Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF-and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD antigen CD256] |
Gene, Accession # | [APRIL], Gene ID: 8741, NCBI: NP_001185552.1, UniProt: O75888 |
Catalog # | MBS9708393 |
Price | $130, $220, $325 |
Order / More Info | APRIL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |