ERCC6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ERCC6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ERCC6 antibody detects endogenous levels of total ERCC6. Function: Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.Subunit Structure: Homodimer. Binds DNA. Interacts with ERCC8. Interacts with a subunit of |
| Immunogen | Immunogen: A synthesized peptide derived from human ERCC6 Subcellular Location: Nucleus. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (92%), Bovine (100%), Sheep (92%), Rabbit (92%), Dog (100%), Chicken (91%), Xenopus (92%) |
| Other Names | [4732403I04; ARMD 5; ARMD5; ATP dependent helicase ERCC6; ATP-dependent helicase ERCC6; C130058G22Rik; CKN 2; CKN2; Cockayne syndrome B protein; Cockayne syndrome group B protein; Cockayne syndrome protein CSB; COFS; COFS1; CS group B correcting; CSB; DNA excision repair protein ERCC 6; DNA excision repair protein ERCC-6; ERCC 6; ERCC6; ERCC6_HUMAN; Excision repair cross complementing rodent repair deficiency, complementation group 6; OTTHUMP00000019581; RAD26; Rad26 homolog; UVSS1] |
| Gene, Accession # | [ERCC6], Gene ID: 2074, NCBI: NP_000115.1, UniProt: Q03468 |
| Catalog # | MBS9609131 |
| Price | $240, $280 |
| Order / More Info | ERCC6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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