RAN Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAN
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionRan is a small GTPase of the Ras family that plays a central role in the spacial and temperal organization of eukaryotic cells. During interphase, Ran-GDP localizes to the cytoplasm and Ran-GTP to the nucleus. This polarized localization of Ran ensures its role in nuclear transport (1). During mitosis, Ran-GTP is chromatin associated, where it promotes spindle assembly and nuclear envolope formation (1, 2). In S phase, Ran-GTP associates with and inhibits MCM helicase, ensuring precise chromosomal DNA duplication during the cell cycle (3).
ImmunogenImmunogen: Recombinant protein of human RAN Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[RAN; ARA24; Gsp1; TC4]
Gene, Accession #[RAN], Gene ID: 5901, NCBI: NP_001287725.1, UniProt: P62826
Catalog #MBS8502463
Price$310
Order / More InfoRAN Antibody from MYBIOSOURCE INC.
Product Specific References1. Quimby, B.B. and Dasso, M. (2003) Curr. Opin. Cell Biol. 15, 338-344. 2. Hetzer, M. et al. (2002) Nat. Cell Biol. 4, 177-184. 3. Yamaguchi, R. and Newport, J. (2003) Cell 113, 115-125.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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