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Antigenic Specificity | CACNA1C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1C subunit play an important rol |
Immunogen | Immunogen: Recombinant Human Voltage-dependent L-type calcium channel subunit alpha-1C protein (1755-1971AA) |
Other Names | [Voltage-dependent L-type calcium channel subunit alpha-1C; Calcium channel; L type; alpha-1 polypeptide; isoform 1; cardiac muscle; Voltage-gated calcium channel subunit alpha Cav1.2; CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1] |
Gene, Accession # | [CACNA1C], Gene ID: 775, NCBI: NP_000710.5, UniProt: Q13936 |
Catalog # | MBS7105221 |
Price | $160, $235 |
Order / More Info | CACNA1C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |