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Antigenic Specificity | Bid (BH3 Domain Specific), 68-103 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 1.855 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Bid antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-103 amino acids from human Bid. Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. |
Immunogen | n/a |
Other Names | [BH3-interacting domain death agonist; p22 BID; BID; BH3-interacting domain death agonist p15; p15 BID; BH3-interacting domain death agonist p13; p13 BID; BH3-interacting domain death agonist p11; p11 BID; BID] |
Gene, Accession # | [BID], Gene ID: 637, NCBI: NP_001187.1, UniProt: P55957 |
Catalog # | MBS9212973 |
Price | $165, $370 |
Order / More Info | Bid (BH3 Domain Specific), 68-103 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wang, X., et al., J. Biol. Chem. 278(31):29184-29191 (2003). Cartron, P.F., et al., Mol. Cell. Biol. 23(13):4701-4712 (2003). Fischer, B., et al., Biochem. Biophys. Res. Commun. 306(2):516-522 (2003). Degli Esposti, M., et al., J. Biol. Chem. 278(18):15749-15757 (2003). Kuwana, T., et al., Cell 111(3):331-342 (2002). |