c-kit Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | c-kit |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of human c-kit. CD117 Antigen, also called KIT or C-kit receptor, is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. |
| Immunogen | n/a |
| Other Names | [mast/stem cell growth factor receptor Kit isoform 1; Mast/stem cell growth factor receptor Kit; mast/stem cell growth factor receptor Kit; KIT proto-oncogene receptor tyrosine kinase; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD_antigen: CD117], [KIT; KIT; PBT; SCFR; C-Kit; CD117; SCFR; SCFR; PBT] |
| Gene, Accession # | [c-kit], Gene ID: 3815, NCBI: NP_000213.1, UniProt: P10721 |
| Catalog # | MBS857152 |
| Price | $280 |
| Order / More Info | c-kit Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Yarden, Y., et al. (1987) EMBO (Eur. Mol. Biot. Organ.) J. 6:3341-3351. 2. Qiu, F. H., et al. (1988) EMBO (Eur. Mol. Biot. Organ.) J. 7:1003-1011. 3. Besmer, et al. 1986. Nature (Lond.). 320:415-421. 4. Zsebo, K. M., et al. (1990) Cell. 63:195-201. 5. Spritz RA, Giebel LB, Holmes SA. (1992) Am J Hum Genet. Feb; 5 (2):261-9. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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