Edit |   |
---|---|
Antigenic Specificity | IPO11 (C-term), 891-920 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 891-920 amino acids from the C-terminal region of human IPO11. IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydro |
Immunogen | n/a |
Other Names | [Importin-11; Imp11; Ran-binding protein 11; RanBP11; IPO11; RANBP11] |
Gene, Accession # | [IPO11], Gene ID: 51194, NCBI: NP_001128251.1, UniProt: Q9UI26 |
Catalog # | MBS9204122 |
Price | $165, $370 |
Order / More Info | IPO11 (C-term), 891-920 Antibody from MYBIOSOURCE INC. |
Product Specific References | Plafker,S.M. et.al., Mol. Cell. Biol. 22 (4), 1266-1275 (2002) |